PATHOLOGY IMPORTANT TOPIC & QUESTIONS FOR SECOND YEAR MBBS, BDS STUDENT 2ND PROFF EXAM

                            PATHOLOGY    

 GENERAL PATHOLOGY

Group-B (COMMENT ON) 

1. Physiological and pathological giant cells are different. (2019 P1)
 2. Cellular changes in irreversible injury. (2018 P1)
 3. Metaplasia is not same as neoplasia. (2018 P1)
 4. Granuloma and granulation tissue. (2017 P1)
 5. Hyperplasia and Hypertrophy are different. (2017 P1)
 6. Direct spread is different from metastasis. (2016 P1) 
7. Role of complements in acute inflammation. (2016 P1)
 8. Thrombus differs from clot. (2015 P1) 
9. Inflammation is beneficial. (2015 P1) 
10. Healing by primary infection versus healing by secondary infection. (2014 P1) 
11. Teratoma and hamartoma are two different lesions. (2014 P1) 
12. Dystrophic versus metastatic calcification. (2014 P1)
 13. Phlebothrombosis and thrombophlebitis are not same. (2013 P1)
 14. Importance of paraneoplastic syndrome. (2013 P1) 
15. Transudate and exudates indicate different clinical conditions. (2012 P1)
 16. Presence of chronic inflammatory cells does not always indicate chronic inflammation; it has other hallmarks too. (2012 P1)
17. Routes of spread of malignant tumours are different. (2012 P2)
 18. Necrosis differs from apoptosis. (2011 P1) 
19. Amyloidosis is the result of long standing chronic diseases. (2011 P1) 
20. Tobacco smoking and diseases. (2010 P1) 
21. Grading and staging of malignant tumours and its relevance. (2010 P1)

Group-C (ANSWER THE FOLLOWING)

 1. Philadelphia chromosome. (2019 P1)

 2. Different between primary and secondary amyloidosis. (2018 P1)

 3. Difference between dystrophic calcification and metastatic calcification. (2018 P1)

 4. Difference between necrosis and apoptosis. (2007 P1) 

5. Healing by primary union and secondary union differ in process of wound healing. (2016 P1)

 6. Pathogenesis of oedema in cardiac disease. (2016 P1) 

7. Difference between coagulative necrosis and liquefactive necrosis. (2015 P1)

 8. Pathogenesis of thrombosis. (2014 P1)

 9. Carcinoma is a multistep process. (2014 P1)

 10. Difference between carcinoma and sarcoma. (2013 P1) 

11. Pathogenesis of amyloidosis. (2013 P1)

 12. Pathogenesis of renal oedema. (2012 P1)

 13. Cause of unconjugated hyperbilirubinemia. (2012 P1)

 14. Antibody dependent cytotoxic cell. (2011 P1) 

15. Difference between carcinoma and sarcoma. (2011 P1) 

16. Arterial and venous thrombosis. (2010 P1) 

17. Transudate and exudates. (2010 P1) 

18. Type III hypersensitivity. (2010 P1)

Group- D (SHORT NOTES)

 1. Type I hypersensitivity reaction. (2019 P1)

 2. BCR-ABL fusion gene. (2019 P1) 

3. Vascular change in acute inflammation. (2018 P1)

 4. Chemical carcinogens (2018 P1)

 5. Klinefelter syndrome (2018 P1)

 6. Tobacco-related human health hazard. (2018 P1) 

7. Langhan’s Giant cell. (2017 P1)

 8. Philadelphia chromosome. (2017 P1)

9. Turner syndrome. (2017 P1)

 10. Septic Shock. (2017 P1)

 11. Radiation injury. (2016 P1)

 12. Hypovolemic shock. (2016 P1)

 13. Transcoelomic space. (2015 P1)

 14. Fine Needle Aspiration Cytology. (2015 P1)

 15. Conjugated hyperbilirubinemia. (2015 P1)

 16. Klinefelter syndrome. (2014 P1) 

17. Decompression sickness. (2014 P1)

 18. Radiation injury. (2014 P1) 

19. Gaucher’s disease. (2013 P1)

 20. Turner syndrome. (2013 P1)

 21. Karyotyping. (2013 P1)

 22. Difference between hypertrophy and hyperplasia. (2012 P1)

 23. Coagulation necrosis. (2012 P1)

 24. Carcinoma in situ. (2012 P2)

 25. Down’s syndrome. (2011 P1)

 26. Carcinoma in-situ. (2011 P1) 

27. Giant cell. (2011 P1)

 28. Dystrophic calcification. (2010 P1)

 29. Apoptosis. (2010 P1)

 30. X-linked disease. (2010 P

HAEMATOLOGY 

Group-A (LONG QUESTIONS)

 1. 30 years old lady presented with hemorrhagic spots in the skin & mucosa, onset is insidious. There is no organomegaly or lymphadenopathy. 2+5+3 (2019 P1) a) What is your provisional diagnosis? b) How will you proceed with diagnosis? c) What is the basic mechanism of this disease?

 2. A 7 years old girl presented with sudden onset of fever, week ness severe pallor, generalized lymphadenopathy, hepatomegaly, sternal tenderness and gum bleeding. 2+6+2 (2018 P1) a) What is provisional diagnosis? b) How will you proceed to confirm the diagnosis? c) What are the important prognostic factors in this case?

 3. A 60 year old male patient with Low back pain and anaemia, X-ray reveals multiple osteolytic lesion. a) What is your provisional diagnosis? 2+8 (2017 P1) b) How will you processed to confirm the diagnosis? 

4. A 45-year-old male with history of partial gastrectomy frequently has anaemia and neurological symptoms. a) What is provisional diagnosis? 2+5+3 (2016 P1) b) How you will proceed to investigation so as to establish your diagnosis? c) Discuss the pathogenesis of this anaemia.

 5. A 7year old male patient presented with fever, pallor, gum bleeding, lymphadenopathy. Peripheral blood, smear revealed fair number of abnormal lymphocytes. 2+6+2 (2015 P1) a) What is your provisional diagnosis? b) How will you diagnose the case in laboratory? c) Enumerate four prognostic factor.

 6. A 4 year old female patient presented with severe pallor and splenomegaly with history of multiple blood transfusion. Biochemical investigation revealed unconjugated hyperbilirubinemia. 2+5+3 (2014 P1) a) What is your provisional diagnosis? b) What is the examination you have done in lab? c) What is the basic genetic defect?